Drug Information

Drug General Information
Drug ID
D0O3NG
Former ID
DNC000564
Drug Name
Dimaprit
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538762]
Structure
Download
2D MOL

3D MOL
Formula
C6H15N3S
InChI
InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)
InChIKey
OLHQOJYVQUNWPL-UHFFFAOYSA-N
CAS Number
CAS 60-00-4
PubChem Compound ID
3077
PubChem Substance ID
5021259, 7979095, 8151956, 11112685, 11113535, 11467011, 11468131, 11486682, 15265190, 16961065, 26751746, 29222222, 47365385, 47662484, 47959949, 48334687, 49699373, 49846697, 49900669, 50901984, 56314095, 57309579, 57321594, 85209056, 85788602, 91567534, 95509074, 96024151, 103124474, 103173420, 104302459, 117373937, 124882517, 124882518, 128825496, 132562708, 134339961, 135008316, 135650186, 137041679, 143456392, 162221383, 162890531, 179236213, 198949187, 221672748, 223446363, 226710935
ChEBI ID
ChEBI:42191
Target and Pathway
Target(s) Histamine H2 receptor Target Info Agonist [551871]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Histamine H2 receptor mediated signaling pathway
PathWhiz Pathway Intracellular Signalling Through Histamine H2 Receptor and Histamine
Gastric Acid Production
Reactome Histamine receptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Secretion of Hydrochloric Acid in Parietal Cells
GPCR ligand binding
GPCR downstream signaling
References
Ref 538762(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1248).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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