Drug General Information
Drug ID	D07TUX
Former ID	DNC007306
Drug Name	7-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527353]
Structure		Download 2D MOL 3D MOL
Formula	C14H12N2O3
Canonical SMILES	C1=CC(=CC2=C1C=CC(=O)O2)OCCN3C=CN=C3
InChI	1S/C14H12N2O3/c17-14-4-2-11-1-3-12(9-13(11)19-14)18-8-7-16-6-5-15-10-16/h1-6,9-10H,7-8H2
InChIKey	JUOCDQIZOPYANC-UHFFFAOYSA-N
PubChem Compound ID	11230598
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[527353]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 527353	J Med Chem. 2004 Dec 30;47(27):6792-803.Design, synthesis, and 3D QSAR of novel potent and selective aromatase inhibitors.
Ref 527353	J Med Chem. 2004 Dec 30;47(27):6792-803.Design, synthesis, and 3D QSAR of novel potent and selective aromatase inhibitors.

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