Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L9YS
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| Former ID |
DCL000184
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| Drug Name |
Octopamine
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| Synonyms |
Analet; Norden; Norfen; Norphen; Norsympathol; Norsympatol; Norsynephrine; Octapamine; Octopamin; Octopamina; Octopaminum; Octopamina [Spanish]; Octopamine [INN]; Octopamine hydrochloride; Octopaminum [Latin]; Paraoxyphenyl aminoethanol; ND 50; TBB066518; WIN 5512; WV 569; Beta-hydroxytyramine; Octopamina [INN-Spanish]; Octopaminum [INN-Latin]; P-Hydroxyphenylethanolamine; P-Norsynephrin; P-Octopamine; Para-Octopamine; Alpha-Aminoethyl-4-hydroxybenzylalkohol; Alpha-(Aminoethyl)-4-hydroxybenzenemethanol; Alpha-(Aminoethyl)-p-hydroxybenzyl alcohol; Alpha-(Aminomethyl)-p-hydroxybenzyl alcohol; Alpha-(aminomethyl)-4-hydroxybenzenemethanol; 1-(p-Hydroxyphenyl)-2-aminoethanol; 4-(2-Amino-1-hydroxyethyl)phenol; 4-Octopamine
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| Drug Type |
Small molecular drug
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| Company |
Sanofi-aventis
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| Structure |
|
Download2D MOL |
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| Formula |
C8H11NO2
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| InChI |
InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2
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| InChIKey |
QHGUCRYDKWKLMG-UHFFFAOYSA-N
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| CAS Number |
CAS 104-14-3
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| PubChem Compound ID | |||||
| PubChem Substance ID |
3135840, 5025344, 8143689, 8152814, 11335420, 11360659, 11363095, 11365657, 11368219, 11371350, 11373803, 11376381, 11461631, 11466977, 11468097, 11483999, 11486813, 11488038, 11490091, 11492217, 11494015, 11537614, 15170928, 26753135, 29223670, 37218827, 47588883, 47588884, 47662158, 47736360, 47810641, 47959617, 47959618, 48110345, 48184885, 48184886, 48334371, 49698899, 49892630, 50105660, 53789379, 57322335, 78819223, 85278819, 89094976, 90341287, 92298134, 99774418, 103235782, 104171205
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| SuperDrug ATC ID |
C01CA18
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| Target and Pathway | |||||
| Target(s) | Coagulation factor Xa | Target Info | Inhibitor | [537045], [537289] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
| Intrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
| Ref 525357 | Juvenile hormone and octopamine in the regulation of division of labor in honey bee colonies. Horm Behav. 2002 Sep;42(2):222-31. | ||||
| Ref 539364 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2149). | ||||
| Ref 537045 | AVE5026, a new hemisynthetic ultra-low-molecular-weight heparin for the prevention of venous thromboembolism in patients after total knee replacement surgery--TREK: a dose-ranging study. J Thromb Haemost. 2009 Apr;7(4):566-72. Epub 2009 Jan 24. | ||||
| Ref 537289 | Description of the chemical and pharmacological characteristics of a new hemisynthetic ultra-low-molecular-weight heparin, AVE5026. J Thromb Haemost. 2009 Jul;7(7):1143-51. Epub 2009 Apr 27. | ||||
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