Drug General Information
Drug ID	D0UK0F
Former ID	DNC010220
Drug Name	6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530400]
Structure		Download 2D MOL 3D MOL
Formula	C9H16N6
Canonical SMILES	CN1CCN(CC1)C2=CC(=NC(=N2)N)N
InChI	1S/C9H16N6/c1-14-2-4-15(5-3-14)8-6-7(10)12-9(11)13-8/h6H,2-5H2,1H3,(H4,10,11,12,13)
InChIKey	RBHNSRTVBDSNLG-UHFFFAOYSA-N
PubChem Compound ID	753256
Target and Pathway
Target(s)	Histamine H4 receptor	Target Info	Inhibitor	[530400]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 530400	Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. Epub 2009 Sep 2.2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
Ref 530400	Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. Epub 2009 Sep 2.2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.

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