TTD | Drug: D08SGV

Drug General Information
Drug ID	D08SGV
Former ID	DIB018649
Drug Name	5-HEAT
Synonyms	5-hydroxyethoxy-N-acetyltryptamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538822]
Structure		Download 2D MOL
Formula	C14H18N2O3
InChI	InChI=1S/C14H18N2O3/c1-10(18)15-5-4-11-9-16-14-3-2-12(8-13(11)14)19-7-6-17/h2-3,8-9,16-17H,4-7H2,1H3,(H,15,18)
InChIKey	CZPLTTWZQPLXMQ-UHFFFAOYSA-N
PubChem Compound ID	10849065
PubChem Substance ID	15891200, 23103373, 42029291, 57375386, 79341936, 103356901, 103961501, 127700853, 135649834, 162484521, 231998154
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Agonist	[525901]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538822	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1345).
Ref 525901	A new melatonin receptor ligand with mt1-agonist and MT2-antagonist properties. J Pineal Res. 2000 Nov;29(4):234-40.

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Drug Information