Drug Information
Drug General Information | |||||
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Drug ID |
D0FG6M
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Former ID |
DCL000385
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Drug Name |
GW642444
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Drug Type |
Small molecular drug
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Company |
GSK
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Structure |
Download2D MOL |
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Formula |
C26H34O7
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Canonical SMILES |
CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O<br />)OC)C
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InChI |
1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1
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InChIKey |
NGGMYCMLYOUNGM-CSDLUJIJSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
12012599, 14760280, 14760282, 17194488, 26757080, 43529088, 49658596, 50669686, 57371639, 85297194, 95689575, 103208677, 104007764, 114786740, 125317249, 134339029, 134340034, 135021824, 137124893, 140059282, 144205619, 144212727, 179150195, 198977418, 210279844, 210282167, 224448724, 226399393, 240218275, 241375601, 249617380, 252156076
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Target and Pathway | |||||
Target(s) | Beta-2 adrenergic receptor | Target Info | Agonist | [550963] | |
NetPath Pathway | TCR Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
References | |||||
Ref 532150 | Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD. PulmPharmacol Ther. 2013 Apr;26(2):256-64. | ||||
Ref 532651 | 2013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9. |
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