Drug General Information
Drug ID
D05EPM
Former ID
DAP000512
Drug Name
Ethotoin
Synonyms
Accenon; Ethotoine; Ethotoinum; Etotoina; Peganone; Pegoanone; Abbott brand of ethotoin; Accenon (TN); Ethotoine [INN-French]; Ethotoinum [INN-Latin]; Etotoina [INN-Spanish]; Peganone (TN); Ethotoin [INN:BAN:JAN]; Ethotoin (JAN/USP/INN); (+-)-3-Ethyl-5-phenylhydantoin; 1-Ethyl-2,5-dioxo-4-phenylimidazolidine; 3-Ethyl-5-phenyl-2,4-imidazolidinedione; 3-Ethyl-5-phenylhydantoin; 3-Ethyl-5-phenylimidazolidin-2,4-dione; 3-ethyl-5-phenylimidazolidine-2,4-dione
Drug Type
Small molecular drug
Indication Complex partial seizures [ICD9: 345.4; ICD10:G40.2] Approved [538439], [542194]
Therapeutic Class
Anticonvulsants
Company
Ovation Pharmaceuticals
Structure
Download
2D MOL

3D MOL

Formula
C11H12N2O2
InChI
InChI=1S/C11H12N2O2/c1-2-13-10(14)9(12-11(13)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,12,15)
InChIKey
SZQIFWWUIBRPBZ-UHFFFAOYSA-N
CAS Number
CAS 86-35-1
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N03AB01
SuperDrug CAS ID
cas=000086351
Target and Pathway
Target(s) Sodium channel protein type 5 subunit alpha Target Info Blocker [536316]
KEGG Pathway Adrenergic signaling in cardiomyocytes
PathWhiz Pathway Muscle/Heart Contraction
Reactome Interaction between L1 and Ankyrins
WikiPathways SIDS Susceptibility Pathways
Cardiac Progenitor Differentiation
References
Ref 538439FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010841.
Ref 542194(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7183).
Ref 536316How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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