Drug General Information
Drug ID
D0S7WX
Former ID
DAP001543
Drug Name
Vitamin A
Synonyms
ACON; ATAV; Afaxin; Agiolan; Agoncal; Alin; Alphalin; Alphasterol; Anatola; Aoral; Apexol; Apostavit; Aquasynth; Atars; Avibon; Avita; Avitol; Axerol; Axerophthol; Axerophtholum; Biosterol; Cylasphere; Dofsol; Epiteliol; LPK; Myvpack; Ophthalamin; Prepalin; Retinol; Retinolo; Retinolum; TROL; Testavol; Thalasphere; Vaflol; Vafol; Veroftal; Vitpex; Vogan; Wachstumsvitamin; Alcovit A; All Trans Retinol; Anatola A; Antixerophthalmic vitamin; Antixerophthalmisches Vitamin; Aquasol A Parenteral; Bentavit A; Chocola A; Disatabs Tabs; Dohyfral A; Homagenets Aoral; Homagenets aorl; Hydrovit A; Lard Factor; Mvc Plus; Oleovitamin A; Plivit A; Retinol solution; Retinolo [DCIT]; Retrovitamin A; Sehkraft A; Super A; Testavol S; Vitamin A alcohol; Vitamin A cryst; Vitamine A; Vitaminum A; Vitavel A; Zinosan N; Rovimix A 500; Vitamin A1; Vitamin A1 alcohol; A-Mulsal; A-Sol; A-Vitan; All-trans retinol; Anti-infective vitamin; Beta-Retinol; Retinol [INN:BAN]; Retinolum [INN-Latin]; Solu-A; Trans-Vitamin A alcohol; Trans-retinol; Vi-Alpha; Vi-a; Vi-alpha; Vio-A; Vitamin A (Feed); Vitamin A (USP); Vitamin A alcohol (VAN); Vitamin A1 alcohol, all trans; Vitamin-A; Vitamin-A alcohol; Vitamin-A alcohol solution; Vitamin-A1; Vitavel-A; Vogan-Neu; Vogan-nu; A-Vi-Pel; ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1); All-trans-Retinol; All-trans-Retinyl alcohol; All-trans-Vitamin A; All-trans-Vitamin A alcohol; All-trans-Vitamin A1; Del-VI-A; Hi-A-Vita; Nio-A-Let; Ro-a-vit; Trans-Retinol acid (Vitamin A); Vi-Dom-A; [11,12-3H]-Retinol; M.V.C. 9+3; M.V.I.-12; Retinol, all-trans-(8CI); Retin-11,12-t2-ol (9CI); Retinol-(cellular-retinol-binding-protein); Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol; All-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol; (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer
Drug Type
Small molecular drug
Indication Night blindness [ICD9: 368.6; ICD10:H53.6] Approved [537623], [540652]
Therapeutic Class
Vitamins
Structure
Download
2D MOL

3D MOL

Formula
C20H30O
InChI
InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChIKey
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
CAS Number
CAS 11103-57-4
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:17336
SuperDrug ATC ID
A11CA01; D10AD02; R01AX02; S01XA02
SuperDrug CAS ID
cas=000068268
Target and Pathway
Target(s) Retinoic acid receptor RXR-gamma Target Info Binder [537623]
Retinoic acid receptor Target Info Binder [537623]
KEGG Pathway PPAR signaling pathway
Thyroid hormone signaling pathway
Adipocytokine signaling pathway
Pathways in cancer
Transcriptional misregulation in cancer
Thyroid cancer
Small cell lung cancer
Non-small cell lung cancer
Pathway Interaction Database Regulation of Androgen receptor activity
RXR and RAR heterodimerization with other nuclear receptor
Retinoic acid receptors-mediated signaling
a6b1 and a6b4 Integrin signaling
Reactome Nuclear Receptor transcription pathway
WikiPathways Vitamin A and Carotenoid Metabolism
Adipogenesis
Nuclear Receptors
References
Ref 537623Vitamins and cofactors: highlights of ESBOC 2009. Nat Chem Biol. 2009 Aug;5(8):530-3.
Ref 540652(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4053).
Ref 537623Vitamins and cofactors: highlights of ESBOC 2009. Nat Chem Biol. 2009 Aug;5(8):530-3.

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