Drug Information
Drug General Information | |||||
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Drug ID |
D02DGU
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Former ID |
DAP001221
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Drug Name |
Tretinoin
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Synonyms |
ATRA; Aberel; Aberela; Acnavit; Airol; Aknefug; Aknoten; Alitretinoin; Atragen; Atralin; Avitoin; Betarretin; Dermairol; Effederm; Eudyna; Lsotretinoin; Nexret; Panretyn; REA; Renova; Retacnyl; Retinoate; Retinova; Solage; TRETINON; Tretinoina; Tretinoine; Tretinoino; Tretinoinum; Vesanoid; Vesnaroid; Vitinoin; Aberela [Norway]; Accutane Roche; Acnavit [Denmark]; All Trans Retinoic Acid; Avita Gel; Avitoin [Norway]; Beta all trans Retinoic Acid; Cordes VAS [Germany]; Cordes vas; Effederm [France]; Isotretinoin Retinoicacid; Panretin Gel; Retin A; Retinoic acid; Retionic acid; Trans Retinoic Acid; Tretin M; Tretinoin Potassium Salt; Tretinoin Sodium Salt; Tretinoin Zinc Salt; Tretinoin liposome; Vitamin A acid; AGN100335; AGN 192013; ALRT 1057; BAL4079; LGD 100057; R 2625; [3H]Retinoic acid; A-Vitaminsyre; A-Vitaminsyre [Denmark]; AT-RA; Aberela (TN); Acid, Retinoic; Acid, Vitamin A; All trans-Retinoic acid; All-trans Retinoic Acid; Alltrans-retinoic acid; Atra-IV; Avita (TN); B-Retinoic acid; BML2-E05; Beta-Ra; Beta-Retinoic acid; Epi-aberel; Potassium Salt, Tretinoin; RETINOIC ACID, ALL TRANS; Renova (TN); Retin A (TN); Retin-A; Retin-A Micro; Retisol-A; Ro 1-5488; Salt, Tretinoin Potassium; Salt, Tretinoin Sodium; Salt, Tretinoin Zinc; Sodium Salt, Tretinoin; Stieva-A; Stieva-a Forte; Trans-Retinoicacid; Tretinoin (TN); Tretinoina [INN-Spanish]; Tretinoine [INN-French]; Tretinoino [INN-Spanish]; Tretinoinum [INN-Latin]; Tri-Luma; Vesanoid (TN); Zinc Salt, Tretinoin; A-Acido (Argentina); Acid A Vit (Belgium, Netherlands); Acid, trans-Retinoic; Acide retinoique (French) (DSL); All-trans-Retinoic acid; All-trans-Tretinoin; All-trans-Vitamin A acid; All-trans-Vitamin A1 acid; PDT-002-002; Retin-A (TN); Stieva-A (TN); Tretinoin 0.1% cream or placebo; Tretinoin [USAN:INN:BAN]; Tretinoin/All-Trans Retinoic Acid; Tretinoine (French) (EINECS); Acid, all-trans-Retinoic; All-(E)-Retinoic acid; All-trans-b-Retinoic acid; All-trans-beta-Retinoic acid; Beta-all-trans-Retinoic acid; Tretinoin (JAN/USP/INN); Acid, beta-all-trans-Retinoic; Retinoic acid, all-trans-(8CI); Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Tretinoin; 15-Apo-beta-caroten-15-oic acid; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; 9(Z)-Retinoic acid; 9-cis-RA
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Drug Type |
Small molecular drug
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Therapeutic Class |
Keratolytic Agents
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Company |
Roche Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C20H28O2
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InChI |
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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InChIKey |
SHGAZHPCJJPHSC-YCNIQYBTSA-N
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CAS Number |
CAS 302-79-4
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PubChem Compound ID | |||||
PubChem Substance ID |
4038, 416403, 596063, 830710, 838467, 841067, 855632, 3138737, 7847162, 7890244, 7980826, 8143163, 8149916, 10299585, 10321438, 11528311, 12014646, 14825303, 14849563, 17405617, 24278674, 24702082, 26612256, 26680099, 26703748, 26716947, 26746936, 26746937, 26759442, 29214999, 31294611, 36887697, 46392576, 46487923, 47216527, 47959456, 47959457, 48110185, 48110186, 48184725, 48184726, 48184727, 48184728, 48258941, 48414424, 48483920, 49698408, 50103969, 50103970, 50126361
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ChEBI ID |
ChEBI:15367
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SuperDrug ATC ID |
D10AD01; L01XX14
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SuperDrug CAS ID |
cas=000302794
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Target and Pathway | |||||
Target(s) | Retinoic acid receptor | Target Info | Binder | [535273] | |
References | |||||
Ref 525348 | Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell. 1991 Aug 23;66(4):663-74. | ||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 539710 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2644). |
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