Drug Information
Drug General Information | |||||
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Drug ID |
D0W5FA
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Former ID |
DIB000021
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Drug Name |
Liposomal lurtotecan
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Synonyms |
OSI-211
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Drug Type |
Small molecular drug
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Indication | Lung cancer [ICD9: 162; ICD10:C33-C34] | Discontinued in Phase 1 | [546810] | ||
Company |
OSI Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C28H30N4O6
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Canonical SMILES |
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC6=C(C=C5N=C4C3=C2)OC<br />CO6)CN7CCN(CC7)C)O
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InChI |
1S/C28H30N4O6/c1-3-28(35)20-11-22-25-18(14-32(22)26(33)19(20)15-38-27(28)34)17(13-31-6-4-30(2)5-7-31)16-10-23-24(12-21(16)29-25)37-9-8-36-23/h10-12,35H,3-9,13-15H2,1-2H3/t28-/m0/s1
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InChIKey |
RVFGKBWWUQOIOU-NDEPHWFRSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | DNA topoisomerase I | Target Info | Inhibitor | [527009] | |
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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