Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O1KX
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| Former ID |
DNC000265
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| Drug Name |
Avasimibe
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| Drug Type |
Small molecular drug
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| Indication | Peripheral vascular disease [ICD9: 443.9; ICD10:I73.9] | Discontinued in Phase 3 | [546526] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C29H43NO4S
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| Canonical SMILES |
CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2<br />C(C)C)C(C)C)C(C)C
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| InChI |
1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
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| InChIKey |
PTQXTEKSNBVPQJ-UHFFFAOYSA-N
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| CAS Number |
CAS 166518-60-1
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10256123, 12014930, 14786561, 17397168, 46240223, 49878439, 51696037, 53789929, 57350929, 93167047, 103111786, 103315998, 103963862, 104253507, 113458560, 117634678, 124757631, 125164435, 125655156, 126661326, 126681655, 128966690, 134339734, 135121138, 135374372, 135727829, 136340367, 136367465, 136920275, 137262947, 137267096, 142549536, 143493389, 144115648, 152053404, 152234929, 152344251, 162011453, 162037802, 162189205, 163908017, 164043012, 174006553, 174527851, 176225440, 179150041, 186014461, 198989658, 223393138, 223536012
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| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Inhibitor | [535439] | |
| KEGG Pathway | Drug metabolism - other enzymes | ||||
| Metabolic pathways | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| References | |||||
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