Drug General Information
Drug ID	D0L6VH
Former ID	DIB005930
Drug Name	BF-389
Drug Type	Small molecular drug
Indication	Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06]		Phase 1	[526850]
Company	Biofor Inc
Structure		Download 2D MOL 3D MOL
Formula	C20H29NO3
Canonical SMILES	C1(=O)/C(=C/c2cc(c(c(C(C)(C)C)c2)O)C(C)(C)C)/CCON1C
CAS Number	CAS 127245-22-1
PubChem Compound ID	6439259
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator	[526850]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 526850	Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8.
Ref 526850	Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8.

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