Drug General Information
Drug ID	D0W0ED
Former ID	DIB009984
Drug Name	Eflucimibe
Synonyms	F-12511
Drug Type	Small molecular drug
Indication	Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78]		Discontinued in Phase 2	[546909]
Company	Pierre Fabre SA
Structure		Download 2D MOL 3D MOL
Formula	C29H43NO2S
Canonical SMILES	c1(NC(=O)[C@H](c2ccccc2)SCCCCCCCCCCCC)c(c(c(c(c1)C)O)C)<br />C
CAS Number	CAS 202340-45-2
PubChem Compound ID	9804740
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Inhibitor	[533663]
KEGG Pathway	Drug metabolism - other enzymes
	Metabolic pathways
Pathway Interaction Database	E2F transcription factor network
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450
References
Ref 546909	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011031)
Ref 533663	Prospects for drug therapy for hyperlipoproteinaemia. Diabete Metab. 1995 Apr;21(2):139-46.

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