Drug General Information
Drug ID	D0B1VQ
Former ID	DIB008785
Drug Name	GR-133347
Synonyms	AH-023
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Terminated	[545477]
Company	Glaxo Group Research Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C1(c2c(CC(NC(=O)C)C1)cccc2)c1ccccc1
CAS Number	CAS 134865-73-9
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Modulator	[550913]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545477	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003420)
Ref 550913	US patent application no. 5,151,446, Substituted 2-amidotetralins as melatonin agonists and antagonists.

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