Drug Information

Drug General Information
Drug ID
D06JWO
Former ID
DIB002664
Drug Name
KT-362
Drug Type
Small molecular drug
Indication Heart arrhythmia [ICD10:I47-I49] Discontinued in Phase 1 [544621]
Company
Kotobuki Pharmaceutical Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C26H32N2O7S
Canonical SMILES
COC1=C(C=C(C=C1)CCNCCC(=O)N2CCCSC3=CC=CC=C32)OC.C(=CC(=<br />O)O)C(=O)O
InChI
1S/C22H28N2O3S.C4H4O4/c1-26-19-9-8-17(16-20(19)27-2)10-12-23-13-11-22(25)24-14-5-15-28-21-7-4-3-6-18(21)24;5-3(6)1-2-4(7)8/h3-4,6-9,16,23H,5,10-15H2,1-2H3;1-2H,(H,5,6)(H,7,8)
InChIKey
YIVXAQUBENUHJC-UHFFFAOYSA-N
CAS Number
CAS 105394-80-7
PubChem Compound ID
119164
PubChem Substance ID
162358594, 163306796
Target and Pathway
Target(s) Calcium channel Target Info Modulator [528634]
References
Ref 544621Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000337)
Ref 528634Comparative cardiac effects of KT-362 and verapamil in isolated heart--correlation to calcium channel current depression. J Cardiovasc Pharmacol. 1991 Oct;18(4):594-604.

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