Drug Information
Drug General Information | |||||
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Drug ID |
D05FFR
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Former ID |
DNC000944
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Drug Name |
MGBG
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C5H12N8
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Canonical SMILES |
CC(=NN=C(N)N)C=NN=C(N)N
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InChI |
1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+
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InChIKey |
MXWHMTNPTTVWDM-NXOFHUPFSA-N
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CAS Number |
CAS 13922-04-8
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PubChem Compound ID | |||||
PubChem Substance ID |
611216, 7888899, 12012645, 15195228, 39377781, 49974828, 51091596, 57361327, 77105216, 85301076, 103504484, 103977023, 113903809, 118049580, 124633349, 126591589, 126688706, 131315453, 132511295, 134340069, 134340223, 134340226, 134973137, 136352263, 137241210, 140630209, 164825287, 179225924, 179226390, 179685434, 223442568, 223670665, 226399648, 227917561, 237032998, 241088157, 249691017, 252559424, 252669978
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SuperDrug ATC ID |
L01XX16
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SuperDrug CAS ID |
cas=000459869
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Target and Pathway | |||||
Target(s) | S-adenosylmethioninedecarboxylase proenzyme | Target Info | Inhibitor | [535032], [535955] | |
NetPath Pathway | EGFR1 Signaling Pathway | ||||
PathWhiz Pathway | Spermidine and Spermine Biosynthesis | ||||
Methionine Metabolism | |||||
WikiPathways | Metabolism of amino acids and derivatives | ||||
References | |||||
Ref 525957 | Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs. Mol Pharmacol. 2001 Feb;59(2):231-8. | ||||
Ref 535793 | S-adenosylmethionine decarboxylase as an enzyme target for therapy. Pharmacol Ther. 1992 Dec;56(3):359-77. |
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