Drug General Information
Drug ID
D04JJE
Former ID
DIB007034
Drug Name
RP-66153
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [545628]
Company
Rhone-Poulenc SA
Structure
Download
2D MOL

3D MOL

Formula
C22H30O2S
Canonical SMILES
c1(c(ccs1)CCCc1ccccc1)CCCCCC(C(=O)O)(C)C
CAS Number
CAS 142422-79-5
PubChem Compound ID
Target and Pathway
Target(s) Leukotriene B4 receptor 1 Target Info Modulator [526746]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 545628Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003980)
Ref 526746Omega-[(omega-arylalkyl)thienyl]alkanoic acids: from specific LTA4 hydrolase inhibitors to LTB4 receptor antagonists. J Med Chem. 1992 Aug 21;35(17):3170-9.

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