Drug Information
Drug General Information | |||||
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Drug ID |
D00YGA
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Former ID |
DIB014466
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Drug Name |
SB-219994
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Synonyms |
SB-219993
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Drug Type |
Small molecular drug
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Company |
SmithKline Beecham plc
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Structure |
Download2D MOL |
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Formula |
C21H21F3N2O5
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InChI |
InChI=1S/C21H21F3N2O5/c1-26(20-25-16-4-2-3-5-17(16)31-20)10-11-29-15-8-6-14(7-9-15)12-18(19(27)28)30-13-21(22,23)24/h2-9,18H,10-13H2,1H3,(H,27,28)/t18-/m1/s1
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InChIKey |
IRAAJHYKQDFNFO-GOSISDBHSA-N
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CAS Number |
CAS 177785-17-0
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Peroxisome proliferator activated receptor gamma | Target Info | Agonist | [527157] | |
PANTHER Pathway | CCKR signaling map ST | ||||
WikiPathways | Wnt Signaling Pathway Netpath | ||||
Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
Differentiation of white and brown adipocyte | |||||
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
Transcriptional Regulation of White Adipocyte Differentiation | |||||
Adipogenesis | |||||
SREBP signalling | |||||
Nuclear Receptors | |||||
References | |||||
Ref 534550 | Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma. J Pharmacol Exp Ther. 1998 Feb;284(2):751-9. | ||||
Ref 539758 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2698). |
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