Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08HFW
|
||||
| Former ID |
DCL000657
|
||||
| Drug Name |
TAK-901
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] | Phase 1 | [548836] | ||
| Company |
Takeda
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C28H32N4O3S
|
||||
| Canonical SMILES |
CCS(=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C3=C2C4=CC(=CN=C4N3)C)<br />C)C(=O)NC5CCN(CC5)C
|
||||
| InChI |
1S/C28H32N4O3S/c1-5-36(34,35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8,13-16,20H,5,9-12H2,1-4H3,(H,29,31)(H,30,33)
|
||||
| InChIKey |
WKDACQVEJIVHMZ-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
24772915, 28725871, 40658123, 124976958, 131549293, 136340315, 136349569, 136367700, 139700564, 152258406, 160647243, 162011362, 162038103, 162202640, 164020967, 164194000, 172914487, 174006378, 174531561, 185979181, 202559448, 223388595, 223704783, 224282669, 226944802, 242060029, 249254536, 251910775, 252109875, 252165326, 252216369
|
||||
| Target and Pathway | |||||
| Target(s) | Aurora kinase B | Target Info | Inhibitor | [551717] | |
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Aurora C signaling | |||||
| FOXM1 transcription factor network | |||||
| Aurora A signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.