Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0DM5A
|
||||
Former ID |
DIB014407
|
||||
Drug Name |
SIM-6080
|
||||
Synonyms |
N1,N2-Dimethyl-N1-[3,3-di(4-fluorophenyl)propyl]-N2-(3,4,5-trimethoxybenzyl)ethylenediamine
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Terminated | [544566] | ||
Structure |
Download2D MOL |
||||
Formula |
C29H36F2N2O3
|
||||
Canonical SMILES |
CN(CCC(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)CCN(C)CC3=CC(=C(C(<br />=C3)OC)OC)OC
|
||||
InChI |
1S/C29H36F2N2O3/c1-32(16-17-33(2)20-21-18-27(34-3)29(36-5)28(19-21)35-4)15-14-26(22-6-10-24(30)11-7-22)23-8-12-25(31)13-9-23/h6-13,18-19,26H,14-17,20H2,1-5H3
|
||||
InChIKey |
NOMSFNRBXCWAIE-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Calcium channel | Target Info | Blocker | [534236], [551871] | |
References | |||||
Ref 534236 | Determination of the calcium antagonist SIM6080 and its N- and O-demethylated metabolites in plasma, urine and tissues by high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):77-85. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.