Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0UH4T
|
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| Former ID |
DCL000832
|
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| Drug Name |
GW-493838
|
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| Drug Type |
Small molecular drug
|
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| Indication | Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] | Discontinued in Phase 2 | [536374] | ||
| Therapeutic Class |
Analgesics
|
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| Company |
GlaxoSmithKline
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H25ClFN7O4
|
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| Canonical SMILES |
CC(C)(C)C1=NN=C(O1)CC2C(C(C(O2)N3C=NC4C3N=CN=C4NC5=C(C=<br />C(C=C5)Cl)F)O)O
|
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| InChI |
1S/C22H25ClFN7O4/c1-22(2,3)21-30-29-14(35-21)7-13-16(32)17(33)20(34-13)31-9-27-15-18(25-8-26-19(15)31)28-12-5-4-10(23)6-11(12)24/h4-6,8-9,13,15-17,19-20,32-33H,7H2,1-3H3,(H,25,26,28)
|
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| InChIKey |
HWYPWMWKJGSTFH-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Adenosine A1 receptor | Target Info | Modulator | [529810] | |
| NetPath Pathway | TCR Signaling Pathway | ||||
| RANKL Signaling Pathway | |||||
| References | |||||
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