Drug Information

Drug General Information
Drug ID
D0LN9P
Former ID
DIB014745
Drug Name
TELUDIPINE HYDROCHLORIDE
Synonyms
BAN; Former USAN >; GR-53992B; GX-1296B; Taludipine hydrochloride < former INNM; Teludipine hydrochloride< Rec INNM; Rac-4-[o-[(E)-2-Carboxyvinyl]phenyl]-2-[(dimethylamino)methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-tert-butyl diethyl ester monohydrochloride; Rac-2-(Dimethylaminomethyl)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1(E)-propenyl]phenyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester monohydrochloride
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Investigative [533748], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C28H39ClN2O6
Canonical SMILES
CCOC(=O)C1=C(C)NC(=C(C1c2ccccc2\\C=C\\C(=O)OC(C)(C)C)C(<br />=O)OCC)CN(C)C
InChI
1S/C28H38N2O6/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6/h11-16,24,29H,9-10,17H2,1-8H3/b16-15+
InChIKey
DKLVJXTUCNPMDC-FOCLMDBBSA-N
CAS Number
CAS 108687-08-7
PubChem Compound ID
9893335
Target and Pathway
Target(s) Calcium channel Target Info Blocker [533748], [551871]
References
Ref 533748Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype. Haematologica. 1994 Jul-Aug;79(4):328-33.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 533748Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype. Haematologica. 1994 Jul-Aug;79(4):328-33.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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