Drug Information
Drug General Information | |||||
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Drug ID |
D07JHJ
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Former ID |
DIB012553
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Drug Name |
IGANIDIPINE HYDROCHLORIDE
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Synonyms |
NKY-722; Iganidipine hydrochloride < Rec INNM >; Rac-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl] 5-methyl diester dihydrochloride
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Drug Type |
Small molecular drug
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Indication | Glaucoma [ICD9: 365; ICD10:H40-H42] | Discontinued in Phase 1 | [544613] | ||
Structure |
Download2D MOL |
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Formula |
C28H38N4O6
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Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OCC(C)(C)CN2CCN(CC2)CC=C)C3=CC(=<br />CC=C3)[N+](=O)[O-])C(=O)OC
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InChI |
1S/C28H38N4O6/c1-7-11-30-12-14-31(15-13-30)17-28(4,5)18-38-27(34)24-20(3)29-19(2)23(26(33)37-6)25(24)21-9-8-10-22(16-21)32(35)36/h7-10,16,25,29H,1,11-15,17-18H2,2-6H3
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InChIKey |
QBTSPDQKRVMTRU-UHFFFAOYSA-N
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CAS Number |
CAS 119687-33-1
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Calcium channel | Target Info | Blocker | [525666], [551871] | |
References | |||||
Ref 525666 | Improving effects of topical administration of iganidipine, a new calcium channel blocker, on the impaired visual evoked potential after endothelin-1 injection into the vitreous body of rabbits. CurrEye Res. 2000 Feb;20(2):101-8. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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