Drug Information
Drug General Information | |||||
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Drug ID |
D0X8XT
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Former ID |
DNCL003441
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Drug Name |
CS-0777
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Drug Type |
Small molecular drug
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Indication | Multiple scierosis [ICD9: 340; ICD10:G35] | Phase 1 | [522226] | ||
Company |
Daiichi Sankyo
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Structure |
Download2D MOL |
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Formula |
C21H30N2O2
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Canonical SMILES |
CC1=CC=C(C=C1)CCCC(=O)C2=CC=C(N2C)CCC(C)(CO)N
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InChI |
1S/C21H30N2O2/c1-16-7-9-17(10-8-16)5-4-6-20(25)19-12-11-18(23(19)3)13-14-21(2,22)15-24/h7-12,24H,4-6,13-15,22H2,1-3H3/t21-/m1/s1
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InChIKey |
YXEQXPNSBUIRDZ-OAQYLSRUSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Sphingosine 1-phosphate receptor 1 | Target Info | Modulator | [531862], [532807] | |
References | |||||
Ref 531862 | Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: results from a 12-week, open-label pilot study in multiple sclerosis patients. J Neuroimmunol. 2012 May 15;246(1-2):100-7. | ||||
Ref 532807 | Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist. ACS Med Chem Lett. 2011 Mar 2;2(5):368-72. |
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