Drug Information
Drug General Information | |||||
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Drug ID |
D0EM4S
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Former ID |
DNCL001608
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Drug Name |
JNJ-39439335
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Drug Type |
Small molecular drug
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Indication | Musculoskeletal pain [ICD9: 338,780; ICD10:R52, G89] | Phase 1 | [523962] | ||
Company |
Johnson & Johnson Pharmaceutical Research & Development
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Structure |
Download2D MOL |
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Formula |
C25H21F3N2O
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Canonical SMILES |
CC(C)(C1=CC=CC=C1C2=CC3=C(C=C2)N=C(N3)C=CC4=CC=C(C=C4)C<br />(F)(F)F)O
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InChI |
1S/C25H21F3N2O/c1-24(2,31)20-6-4-3-5-19(20)17-10-13-21-22(15-17)30-23(29-21)14-9-16-7-11-18(12-8-16)25(26,27)28/h3-15,31H,1-2H3,(H,29,30)/b14-9+
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InChIKey |
ORDHXXHTBUZRCN-NTEUORMPSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Vanilloid receptor 1 | Target Info | Antagonist | [533205] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References |
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