Drug Information
Drug General Information | |||||
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Drug ID |
D0XS4X
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Former ID |
DIB015991
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Drug Name |
Ibodutant
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Synonyms |
MEN-15596; Tachykinin NK2 receptor antagonist (irritable bowel syndrome), Menarini
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Drug Type |
Small molecular drug
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Company |
The Menarini Group
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Structure |
Download2D MOL |
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Formula |
C37H48N4O4S
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InChI |
InChI=1S/C37H48N4O4S/c1-26-9-10-30-23-33(46-32(30)21-26)35(43)40-37(15-5-6-16-37)36(44)39-31(22-27-7-3-2-4-8-27)34(42)38-24-28-11-17-41(18-12-28)25-29-13-19-45-20-14-29/h2-4,7-10,21,23,28-29,31H,5-6,11-20,22,24-25H2,1H3,(H,38,42)(H,39,44)(H,40,43)/t31-/m1/s1
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InChIKey |
YQYSVMKCMIUCHY-WJOKGBTCSA-N
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CAS Number |
CAS 522664-63-7
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | NK-2 receptor | Target Info | Antagonist | [532668] | |
Reactome | G alpha (q) signalling events | ||||
References | |||||
Ref 525030 | ClinicalTrials.gov (NCT02320318) 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D). U.S. National Institutes of Health. | ||||
Ref 539341 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2117). |
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