Drug General Information
Drug ID	D08BEA
Former ID	DCL000850
Drug Name	Ipamorelin
Drug Type	Small molecular drug
Indication	Postoperative ileus [ICD9: 537.2, 560.1, 560.31, 777.1, 777.4; ICD10:K31.5, K56.0, K56.3, K56.7, P76.1]		Phase 1/2	[536527]
Company	Sapphire therapeutics
Structure		Download 2D MOL
Formula	C38H49N9O5
CAS Number	CAS 170851-70-4
PubChem Compound ID	20754357
Target and Pathway
Target(s)	Growth hormone secretagogue receptor type 1	Target Info	Modulator
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
NetPath Pathway	Leptin Signaling Pathway
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 536527	Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26.

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