Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y6ZK
|
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| Former ID |
DNC000764
|
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| Drug Name |
IB-MECA
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C18H19IN6O4
|
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| InChI |
InChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1
|
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| InChIKey |
HUJXGQILHAUCCV-MOROJQBDSA-N
|
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| CAS Number |
CAS 152918-18-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7978518, 10240823, 12014966, 14884738, 14909248, 24277717, 26752055, 26752056, 29303901, 50068252, 50104709, 53789321, 56463617, 57340522, 75764681, 90341246, 91704557, 103344811, 104012075, 104419080, 124800870, 126671545, 128114796, 134340105, 135080042, 135650362, 135653740, 135698154, 140688645, 162169281, 162226817, 163123389, 171579213, 175427023, 188627623, 198971672, 204371128, 223660144, 226783446, 241182098, 241375196, 250124320, 252215560, 252432477, 252450996
|
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| Target and Pathway | |||||
| Target(s) | Adenosine A3 receptor | Target Info | Agonist | [535470] | |
| References | |||||
| Ref 467554 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 422). | ||||
| Ref 527444 | CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model. Neoplasia. 2005 Jan;7(1):85-90. | ||||
| Ref 528521 | Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. Arthritis Res Ther. 2006;8(6):R169. | ||||
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