Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0LJ8C
|
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| Former ID |
DNCL001875
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| Drug Name |
LCZ696
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| Drug Type |
Small molecular drug
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| Indication | Heart failure [ICD9: 428; ICD10:I50] | Approved | [533123] | ||
| Company |
Novartis Pharmaceuticals
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| Structure |
|
Download2D MOL |
|||
| Formula |
C48H64N6Na3O11+3
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| Canonical SMILES |
CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C<br />(=O)O.CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CC<br />C(=O)O.O.O.O.[Na+].[Na+].[Na+]
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| InChI |
1S/C24H29N5O3.C24H29NO5.3Na.3H2O/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23;1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;;;;;;/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28);4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);;;;3*1H2/q;;3*+1;;;/t22-;17-,21+;;;;;;/m01....../s1
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| InChIKey |
ACXLNSLRLQLEAL-HWSDWTSLSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Neutral endopeptidase | Target Info | Modulator | [533123] | |
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | |||||
| References | |||||
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