Drug Information
Drug General Information | |||||
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Drug ID |
D06GDH
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Former ID |
DCL000763
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Drug Name |
DA-5018
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Synonyms |
Capsavanil; Davasaicin; Da 5018; KR-25018; Benzeneacetamide, 4-(2-aminoethoxy)-N-(3-(3,4-dimethylphenyl)propyl)-3-methoxy-, monohydrochloride; 2-[4-(2-aminoethoxy)-3-methoxyphenyl]-N-[3-(3,4-dimethylphenyl)propyl]acetamide; 2-[4-(2-aminoethoxy)-3-methoxyphenyl]-N-[3-(3,4-dimethylphenyl)propyl]acetamide hydrochloride
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Drug Type |
Small molecular drug
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Indication | Diabetic neuropathy; Postherpetic neuralgia [ICD9: 053.19, 250, 250.6, 356.0, 356.8; ICD10:E11.21, G44.847, G53.0, G64, G90.0] | Discontinued in Phase 2 | [536374] | ||
Company |
Dong-A
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Structure |
Download2D MOL |
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Formula |
C22H30N2O3
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Canonical SMILES |
CC1=C(C=C(C=C1)CCCNC(=O)CC2=CC(=C(C=C2)OCCN)OC)C
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InChI |
1S/C22H30N2O3/c1-16-6-7-18(13-17(16)2)5-4-11-24-22(25)15-19-8-9-20(27-12-10-23)21(14-19)26-3/h6-9,13-14H,4-5,10-12,15,23H2,1-3H3,(H,24,25)
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InChIKey |
VVMIHZHLNJMAQP-UHFFFAOYSA-N
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CAS Number |
CAS 147497-64-1
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Vanilloid receptor 1 | Target Info | Modulator | [1572591] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References |
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