Drug General Information
Drug ID	D03NDI
Former ID	DIB014559
Drug Name	KCO-912
Indication	Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47]		Discontinued in Phase 2	[547581]
Company	Novartis AG
Structure		Download 2D MOL 3D MOL
Canonical SMILES	S(=O)(=O)(c1cc2[C@@H](N3C(=O)CCCC3)[C@@H](C(Oc2cc1)(C)C<br />)O)Nc1ccccc1
Target and Pathway
Target(s)	Potassium channel	Target Info	Agonist	[526289]
References
Ref 547581	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017535)
Ref 526289	KCO912: a potent and selective opener of ATP-dependent potassium (K(ATP)) channels which suppresses airways hyperreactivity at doses devoid of cardiovascular effects. Naunyn Schmiedebergs Arch Pharmacol. 2002 Mar;365(3):220-30. Epub 2002 Jan 23.

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