Drug General Information
Drug ID	D0Z1TF
Former ID	DIB005785
Drug Name	Ro-25-4094
Drug Type	Small molecular drug
Indication	Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25]		Terminated	[545933]
Company	Roche Holding AG
Structure		Download 2D MOL 3D MOL
Formula	C33H44O8
Canonical SMILES	c12c(C(=O)CCO2)ccc(c1CCC)OCCCCCCc1c(CCC(=O)O)c(OCCCCCC(<br />=O)O)ccc1
CAS Number	CAS 150596-99-9
PubChem Compound ID	9850974
Target and Pathway
Target(s)	Leukotriene B4 receptor 1	Target Info	Modulator	[545934]
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
Reactome	Leukotriene receptors
	G alpha (q) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545933	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005401)
Ref 545934	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005401)

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