Drug Information
Drug General Information | |||||
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Drug ID |
D0CG0G
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Former ID |
DIB008924
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Drug Name |
11beta-hydroxysteroid dehydrogenase-1 (HSD1) inhibitors
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Synonyms |
11beta-HSD1 inhibitors (metabolic disorders), Merck
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Indication | Atherosclerosis [ICD9: 414.0, 440; ICD10:I70] | Investigative | [552025] | ||
Company |
Merck & Co Inc
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Structure |
Download2D MOL |
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Canonical SMILES |
O=S(=O)(CC[C@]12CC[C@](c3n(c(nn3)c3ccccc3C(F)(F)F)C)(CC<br />1)CC2)CC
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Target and Pathway | |||||
Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [543704] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
FSH Signaling Pathway | |||||
PathWhiz Pathway | Steroidogenesis | ||||
Reactome | Glucocorticoid biosynthesis | ||||
References |
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