Drug Information

Drug General Information
Drug ID
D06MWU
Former ID
DIB008049
Drug Name
LUF-5833
Synonyms
A3 adenosine receptor allosteric enhancers (ischemia); LUF-5833; LUF-6000; LUF-6096; A3 adenosine receptor allosteric enhancers (ischemia), NIH/University of Leiden
Indication Ischemia [ICD9: 459.89; ICD10:I99.8] Investigative [543555]
Company
Leiden; Amsterdam Center for Drug Research
Structure
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2D MOL

3D MOL
Canonical SMILES
c1ccc2c(c1)c(cc(n2)Nc1cc(c(cc1)Cl)Cl)NC(=O)C1CCCCC1
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Enhancer [543555]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 543555(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 21).
Ref 543555(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 21).

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