Drug Information
Drug General Information | |||||
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Drug ID |
D0Q3ES
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Former ID |
DCL000051
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Drug Name |
APD668
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Drug Type |
Small molecular drug
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Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Discontinued in Phase 1 | [548256] | ||
Company |
Arena Pharma.
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Structure |
Download2D MOL |
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Formula |
C19H23N5O3S
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Canonical SMILES |
C1CN(CCN1CCCCN2C(=O)C3=CC=CC=C3S2(=O)=O)C4=NC=CC=N4
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InChI |
1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2
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InChIKey |
TZJUVVIWVWFLCD-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7603533, 8184984, 11114236, 12013978, 14903693, 43114717, 47285840, 47731233, 49883567, 50326777, 57313863, 85209405, 85788167, 91746214, 103166960, 103918673, 104311449, 104827256, 117598635, 119525529, 129335952, 134338757, 134340130, 135015567, 135650411, 135698194, 137231966, 142141651, 144204513, 162023316, 162222165, 163135249, 170466380, 175611931, 179151468, 184536638, 198972236, 202544113, 224910665, 226458694, 252156151, 252330661, 252450956, 252562161
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Target and Pathway | |||||
Target(s) | Glucose-dependent insulinotropic receptor | Target Info | Agonist | [551535] | |
KEGG Pathway | cAMP signaling pathway | ||||
Insulin secretion | |||||
WikiPathways | Incretin Synthesis, Secretion, and Inactivation | ||||
References |
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