Drug Information
Drug General Information | |||||
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Drug ID |
D0WX3N
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Former ID |
DIB011238
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Drug Name |
KRP-110
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Synonyms |
IDDBCP262221
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Indication | Constipation [ICD9: 564; ICD10:K59.0] | Investigative | [1] | ||
Company |
Kyorin Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Canonical SMILES |
C1(CCN(CC1)CCC(C1CCCCC1)O)N(C(=O)c1occc1)c1ccc(cn1)C
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Target and Pathway | |||||
Target(s) | Mu-type opioid receptor | Target Info | Modulator | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Estrogen signaling pathway | |||||
Morphine addiction | |||||
NetPath Pathway | TCR Signaling Pathway | ||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Enkephalin release | |||||
Pathway Interaction Database | IL4-mediated signaling events | ||||
Reactome | Peptide ligand-binding receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | TCR Signaling Pathway | ||||
GPCRs, Class A Rhodopsin-like | |||||
Peptide GPCRs | |||||
Opioid Signalling | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 319). | ||||
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