Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09PPG
|
||||
| Former ID |
DIB007257
|
||||
| Drug Name |
Metformin arginine-hemisuccinimide
|
||||
| Synonyms |
Metformin; Diap-2; Metformin arginine-hemisuccinate-hemisuccinamide; Metformin arginine-hemisuccinimide (type 2 diabetes); Diap-2 (type 2 diabetes), Arteria; Metformin arginine-hemisuccinimide (type 2 diabetes), Arteria
|
||||
| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Approved | [550096] | ||
| Company |
Boehringer Ingelheim Pharmaceuticals; Merck; Depomed; Janssen Research & Development; AstraZeneca; Bristol-Myers Squibb
|
||||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
C(=N)(NC(=N)N(C)C)N.C(CC(=O)O)C(=O)NC(=N)NCCC[C@H](N)C(<br />=O)O
|
||||
| CAS Number |
CAS 657-24-9
|
||||
| Target and Pathway | |||||
| Target(s) | Insulin receptor | Target Info | Inhibitor | [527070] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| cGMP-PKG signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| FoxO signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Adherens junction | |||||
| Insulin signaling pathway | |||||
| Ovarian steroidogenesis | |||||
| Type II diabetes mellitus | |||||
| Non-alcoholic fatty liver disease (NAFLD) | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by PTP1B | |||||
| Signaling events mediated by TCPTP | |||||
| Insulin-mediated glucose transport | |||||
| PathWhiz Pathway | Insulin Signalling | ||||
| Leucine Stimulation on Insulin Signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.