Drug Information

Drug General Information
Drug ID
D0U5TL
Former ID
DIB006999
Drug Name
Plavix
Synonyms
P2Y12 antagonists (thrombosis); P2Y12 antagonists (thrombosis), Pfizer
Drug Type
Small molecular drug
Indication Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Approved [543771]
Company
Pfizer Inc
Structure
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2D MOL

3D MOL
Formula
C16H16ClNO2S
Canonical SMILES
C1N(CCN(C1)C(=O)[C@H](CCC(=O)O)NC(=O)c1nc(nc(c1)N1CCC(C<br />C1)C(=O)N(CC)CC)c1ccccc1)C(=O)OCCCCC
PubChem Compound ID
60606
Target and Pathway
Target(s) P2Y purinoceptor 12 Target Info Antagonist [543771]
KEGG Pathway Platelet activation
Reactome P2Y receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 543771(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328).
Ref 543771(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328).

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