Drug Information
Drug General Information | |||||
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Drug ID |
D0V8RY
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Former ID |
DIB009365
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Drug Name |
KR-30450
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Synonyms |
SKP-450; 1-[2(R)-(1,3-Dioxolan-2-yl)-2-methyl-6-nitro-2H-1-benzopyran-4-yl]pyrrolidin-2-one
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Discontinued in Phase 1 | [545884] | ||
Structure |
Download2D MOL |
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CAS Number |
CAS 146822-06-2
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Target and Pathway | |||||
Target(s) | Potassium channel | Target Info | Opener | [531635], [534585] | |
References | |||||
Ref 531635 | Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012 Jan;40(Database issue):D1128-36. | ||||
Ref 534585 | Cardioprotective effects of KR-30450, a novel K+(ATP) opener, and its major metabolite KR-30818 on isolated rat hearts. Jpn J Pharmacol. 1998 Jan;76(1):65-73. |
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