Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08VAR
|
||||
| Former ID |
DIB015100
|
||||
| Drug Name |
APH-0812
|
||||
| Synonyms |
Bryostatin-1 + HDAC inhibitor combination (HIV-1 infection), Aphios
|
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| Indication | HIV-1 infection [ICD9: 001-139, 042; ICD10:B20-B24] | Phase 2 | [1], [2] | ||
| Company |
Aphios Corp
|
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| Target and Pathway | |||||
| Target(s) | Protein kinase C | Target Info | Inhibitor | [1], [2] | |
| Histone deacetylase | Target Info | Inhibitor | [1], [2] | ||
| References | |||||
| REF 1 | Bryostatin-1: a novel PKC inhibitor in clinical development. Cancer Invest. 2003;21(6):924-36. | ||||
| REF 2 | Targeting the protein kinase C family: are we there yet. Nat Rev Cancer. 2007 Jul;7(7):554-62. | ||||
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