Drug Information
Drug General Information | |||||
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Drug ID |
D0D4ZW
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Former ID |
DIB003254
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Drug Name |
EGS-21
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Synonyms |
Glucocerebroside, Enzo; Glucosylceramide, Enzo Biochem
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Drug Type |
Small molecular drug
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Indication | Crohn's disease [ICD9: 555; ICD10:K50] | Phase 2 | [547959] | ||
Company |
Enzo Biochem Inc
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Structure |
Download2D MOL |
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Formula |
C48H93NO8
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Canonical SMILES |
CCCCCCCCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)O)O)O)<br />C(C=CCCCCCCCCCCCCC)O
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InChI |
1S/C48H93NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h35,37,41-43,45-48,50-51,53-55H,3-34,36,38-40H2,1-2H3,(H,49,52)/b37-35+/t41-,42+,43+,45+,46-,47+,48+/m0/s1
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InChIKey |
POQRWMRXUOPCLD-GZXCKHLVSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Insulin receptor | Target Info | Modulator | [532546] | |
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
cGMP-PKG signaling pathway | |||||
HIF-1 signaling pathway | |||||
FoxO signaling pathway | |||||
PI3K-Akt signaling pathway | |||||
AMPK signaling pathway | |||||
Adherens junction | |||||
Insulin signaling pathway | |||||
Ovarian steroidogenesis | |||||
Type II diabetes mellitus | |||||
Non-alcoholic fatty liver disease (NAFLD) | |||||
Aldosterone-regulated sodium reabsorption | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Insulin Pathway | ||||
Signaling events mediated by PTP1B | |||||
Signaling events mediated by TCPTP | |||||
Insulin-mediated glucose transport | |||||
PathWhiz Pathway | Insulin Signalling | ||||
Leucine Stimulation on Insulin Signaling | |||||
References |
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