Target General Information
Target ID	T01908
Target Name	Tissue kallikrein
Synonyms	Glandular kallikrein; KLK; Kallikrein; hGK; KLK2
Target Type	Discontinued
Gene Name	KLK1
Biochemical Class	Peptidase
UniProt ID	KLK1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Atopic dermatitis
Example drug	Dermolastin			Discontinued in Phase 2	[547642], [1572592]
Tissue	Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.02 Z-score: -0.20 P-value: 2.30E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 547642	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018071)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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