Target expression details
Target General Information | |||||
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Target ID | T21945 | ||||
Target Name | Norepinephrine transporter | ||||
Synonyms | NET; Norepinephrine transporter; SLC6A2 | ||||
Target Type | Successful | ||||
Gene Name | SLC6A2 | ||||
Biochemical Class | Neurotransmitter:sodium symporter | ||||
UniProt ID | SC6A2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Depression | ||||
Example drug | Trimipramine | Approved | [1], [2] | ||
Tissue | Pre-frontal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 7.02E-03 Z-score: 0.07 P-value: 7.05E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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