Target General Information
Target ID T37848
Target Name Albendazole monooxygenase
Synonyms Albendazole monooxygenase; Albendazole sulfoxidase; CYP3A3; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; HLp; NF-25; Nifedipine oxidase; P450-PCN1; Quinine 3-monooxygenase; Taurochenodeoxycholate 6-alpha-hydroxylase; CYP3A4
Target Type Clinical Trial
Gene Name CYP3A4
Biochemical Class Oxidoreductases acting on paired donors
UniProt ID CP3A4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Liver cancer
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -3.12
Z-score: -2.25
P-value: 1.02E-14
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -2.99
Z-score: -4.75
P-value: 1.09E-84
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Myeloma
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.62
Z-score: -2.64
P-value: 1.93E-04
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
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