Target expression details
Target General Information | |||||
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Target ID | T43739 | ||||
Target Name | Peripheral nerve sodium channel 3 | ||||
Synonyms | PN3; SNS; TTX-R sodium channel; TTX-R/NaV1.8; Transient tetrodotoxin-resistant Na+ current; Voltage-gated sodium channel NaV1.8; SCN10A | ||||
Target Type | Successful | ||||
Gene Name | SCN10A | ||||
Biochemical Class | Sodium channel | ||||
UniProt ID | SCNAA_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | Corus 1030 | Discontinued in Phase 2 | [547604], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.16 Z-score: -0.31 P-value: 9.89E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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