Target General Information
Target ID T50066
Target Name Chloride channel protein 2
Synonyms ClC-2; ClC-2 Cl- channel; ClC-2 chloride channel; CLCN2
Target Type Successful
Gene Name CLCN2
Biochemical Class Chloride channel
UniProt ID CLCN2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Alopecia
Example drug RK-023 Phase 2 [548944], [1572592]
Tissue Skin from scalp
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.01
Z-score: -0.06
P-value: 8.78E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Irritable bowel syndrome
Tissue Rectal colon tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.35
Z-score: -0.62
P-value: 9.63E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref
Ref 548944Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030641)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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