Target expression details
Target General Information | |||||
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Target ID | T50066 | ||||
Target Name | Chloride channel protein 2 | ||||
Synonyms | ClC-2; ClC-2 Cl- channel; ClC-2 chloride channel; CLCN2 | ||||
Target Type | Successful | ||||
Gene Name | CLCN2 | ||||
Biochemical Class | Chloride channel | ||||
UniProt ID | CLCN2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Alopecia | ||||
Example drug | RK-023 | Phase 2 | [548944], [1572592] | ||
Tissue | Skin from scalp | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.01 Z-score: -0.06 P-value: 8.78E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Irritable bowel syndrome | ||||
Tissue | Rectal colon tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.35 Z-score: -0.62 P-value: 9.63E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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