TTD | Expression Details

Target General Information
Target ID	T53378
Target Name	Carbonic anhydrase IV
Synonyms	CAIV; Carbonate dehydratase IV; Carbonic anhydrase 4; CA4
Target Type	Successful
Gene Name	CA4
Biochemical Class	Carbon-oxygen lyases
UniProt ID	CAH4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Breast cancer
Example drug	COUMATE			Phase 2	[531371], [1572592]
Tissue	Breast tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -2.02 Z-score: -1.77 P-value: 1.58E-77
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: -1.46 Z-score: -1.44 P-value: 4.08E-14
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 531371	Irosustat: a first-generation steroid sulfatase inhibitor in breast cancer. Expert Rev Anticancer Ther. 2011 Feb;11(2):179-83.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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