TTD | Expression Details

Target General Information
Target ID	T54132
Target Name	Voltage-gated potassium channel KvLQT3
Synonyms	K+ channel KCNQ3; KQT-like 3; Potassium channel KQT-like 3; Potassium channel alpha subunit KvLQT3; Voltage-gated potassium channel subunit Kv7.3; KCNQ3
Target Type	Successful
Gene Name	KCNQ3
Biochemical Class	Voltage-gated ion channel
UniProt ID	KCNQ3_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Epilepsy
Example drug	Retigabine			Approved	[536934], [539679], [1572592]
Tissue	Peritumoral cortex tissue
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of the persons with other diseases not directly affecting the tissue
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 539679	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2601).
Ref 536934	Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. Epub 2008 Nov 12.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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