Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T55285 | ||||
| Target Name | Glycine receptor | ||||
| Synonyms | GLR; Glycine receptor 58 kDa subunit; GLRB | ||||
| Target Type | Successful | ||||
| Gene Name | GLRB | ||||
| Biochemical Class | Neurotransmitter receptor | ||||
| UniProt ID | GLRB_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Epilepsy | ||||
| Example drug | MDL-27531 | Phase 1 | [1], [2] | ||
| Tissue | Peritumoral cortex tissue | ||||
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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| Reference | |||||
| REF 1 | MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord. Neurosci Lett. 1992 Nov 23;147(1):101-5. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. | ||||
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