Target expression details
Target General Information | |||||
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Target ID | T62184 | ||||
Target Name | Sodium- and chloride-dependent GABA transporter 1 | ||||
Synonyms | GABA transporter 1; SLC6A1 | ||||
Target Type | Successful | ||||
Gene Name | SLC6A1 | ||||
Biochemical Class | Neurotransmitter:sodium symporter | ||||
UniProt ID | SC6A1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Myeloma | ||||
Example drug | Metadoxine | Approved | [524626], [531706], [1572592] | ||
Tissue | Bone marrow | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.24 Z-score: -0.62 P-value: 4.99E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 531706 | Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease. Hum Psychopharmacol. 2011 Dec;26(8):554-9. |
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